BDBM50100299 CHEMBL423109::N-[3-(2-Cyano-5-imidazol-1-ylmethyl-phenoxy)-phenyl]-benzamide

SMILES O=C(Nc1cccc(Oc2cc(Cn3ccnc3)ccc2C#N)c1)c1ccccc1

InChI Key InChIKey=PCEQFKLIONHDSE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100299   

LigandPNGBDBM50100299(N-[3-(2-Cyano-5-imidazol-1-ylmethyl-phenoxy)-pheny...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50100299(N-[3-(2-Cyano-5-imidazol-1-ylmethyl-phenoxy)-pheny...)
Affinity DataIC50: 38nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed