BDBM50100295 4-Imidazol-1-ylmethyl-2-(4-methoxy-phenoxy)-benzonitrile::CHEMBL279066

SMILES COc1ccc(Oc2cc(Cn3ccnc3)ccc2C#N)cc1

InChI Key InChIKey=QBCDCFPXBYGDJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100295   

LigandPNGBDBM50100295(4-Imidazol-1-ylmethyl-2-(4-methoxy-phenoxy)-benzon...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50100295(4-Imidazol-1-ylmethyl-2-(4-methoxy-phenoxy)-benzon...)
Affinity DataIC50: 290nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed