BDBM50100286 4-Imidazol-1-ylmethyl-2-(naphthalen-2-yloxy)-benzonitrile::CHEMBL22959

SMILES N#Cc1ccc(Cn2ccnc2)cc1Oc1ccc2ccccc2c1

InChI Key InChIKey=BECWPNYJZIVGFM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100286   

LigandPNGBDBM50100286(4-Imidazol-1-ylmethyl-2-(naphthalen-2-yloxy)-benzo...)
Affinity DataIC50: 520nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50100286(4-Imidazol-1-ylmethyl-2-(naphthalen-2-yloxy)-benzo...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed