BDBM50100276 2-(2,5-Dimethoxy-phenoxy)-4-imidazol-1-ylmethyl-benzonitrile::CHEMBL22854

SMILES COc1ccc(OC)c(Oc2cc(Cn3ccnc3)ccc2C#N)c1

InChI Key InChIKey=YOPYNAOWKGCZRK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50100276   

LigandPNGBDBM50100276(2-(2,5-Dimethoxy-phenoxy)-4-imidazol-1-ylmethyl-be...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of rate of incorporation of [3H]GGPP into a biotinylated peptide corresponding to C-terminus of human Ki-Ras by human geranylgeranyl-trans...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50100276(2-(2,5-Dimethoxy-phenoxy)-4-imidazol-1-ylmethyl-be...)
Affinity DataIC50: 100nMAssay Description:Inhibition of rate of incorporation of [3H]FPP into recombinant Ras-CVIM by human farnesyltransferase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed