BDBM50100258 2-Amino-5-[(3,5-dichloro-phenylamino)-methyl]-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one::CHEMBL61108

SMILES Nc1nc2[nH]cc(CNc3cc(Cl)cc(Cl)c3)c2c(=O)[nH]1

InChI Key InChIKey=BXABQMLCAOIJKE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50100258   

TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50100258(2-Amino-5-[(3,5-dichloro-phenylamino)-methyl]-3,7-...)
Affinity DataIC50: 6.62E+4nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50100258(2-Amino-5-[(3,5-dichloro-phenylamino)-methyl]-3,7-...)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50100258(2-Amino-5-[(3,5-dichloro-phenylamino)-methyl]-3,7-...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed