BDBM50100254 2-Amino-5-{[(3,5-dimethoxy-phenyl)-methyl-amino]-methyl}-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one::CHEMBL61415

SMILES COc1cc(OC)cc(c1)N(C)Cc1c[nH]c2nc(N)[nH]c(=O)c12

InChI Key InChIKey=OCXYEJHNXDBUPU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50100254   

TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50100254(2-Amino-5-{[(3,5-dimethoxy-phenyl)-methyl-amino]-m...)
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50100254(2-Amino-5-{[(3,5-dimethoxy-phenyl)-methyl-amino]-m...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50100254(2-Amino-5-{[(3,5-dimethoxy-phenyl)-methyl-amino]-m...)
Affinity DataIC50: 8.70E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed