BDBM50100248 2-Amino-5-[(2,5-dimethoxy-phenylamino)-methyl]-3,7-dihydro-pyrrolo[2,3-d]pyrimidin-4-one::CHEMBL302633

SMILES COc1ccc(OC)c(NCc2c[nH]c3nc(N)[nH]c(=O)c23)c1

InChI Key InChIKey=FCUFYNIKWJPINF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50100248   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50100248(2-Amino-5-[(2,5-dimethoxy-phenylamino)-methyl]-3,7...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50100248(2-Amino-5-[(2,5-dimethoxy-phenylamino)-methyl]-3,7...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of rat liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Pneumocystis carinii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50100248(2-Amino-5-[(2,5-dimethoxy-phenylamino)-methyl]-3,7...)
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibitory activity against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed