BDBM50100095 2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-N-hydroxy-acetamide::CHEMBL298647

SMILES ONC(=O)CN1Cc2c(Cl)cccc2NC1=O

InChI Key InChIKey=OMZKWXAFDODBPH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50100095   

TargetMacrophage metalloelastase(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human macrophage elastase, matrix metalloproteinase-12 (MMP-12).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEndothelin-converting enzyme 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition against endothelin-converting enzyme.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAngiotensin-converting enzyme(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition against angiotensin I converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeprilysin(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition against neutral endopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeptide deformylase(Escherichia coli (strain K12))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50: 310nMAssay Description:Inhibition of the isolated native E. coli peptide deformylase (PDF)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50100095(2-(5-Chloro-2-oxo-1,4-dihydro-2H-quinazolin-3-yl)-...)
Affinity DataIC50: 460nMAssay Description:Inhibition of Collagenase-3, matrix metalloptroteinase-13 (MMP-13).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed