BDBM50100089 2-(4-Benzoyl-benzenesulfonylmethyl)-5-phenyl-pentanoic acid hydroxyamide::CHEMBL34206

SMILES ONC(=O)C(CCCc1ccccc1)CS(=O)(=O)c1ccc(cc1)C(=O)c1ccccc1

InChI Key InChIKey=SYAAEFMNVNGONW-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50100089   

TargetStromelysin-1(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100089(2-(4-Benzoyl-benzenesulfonylmethyl)-5-phenyl-penta...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100089(2-(4-Benzoyl-benzenesulfonylmethyl)-5-phenyl-penta...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100089(2-(4-Benzoyl-benzenesulfonylmethyl)-5-phenyl-penta...)
Affinity DataIC50: 4nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100089(2-(4-Benzoyl-benzenesulfonylmethyl)-5-phenyl-penta...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100089(2-(4-Benzoyl-benzenesulfonylmethyl)-5-phenyl-penta...)
Affinity DataIC50: 5nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100089(2-(4-Benzoyl-benzenesulfonylmethyl)-5-phenyl-penta...)
Affinity DataIC50: 4nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50100089(2-(4-Benzoyl-benzenesulfonylmethyl)-5-phenyl-penta...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100089(2-(4-Benzoyl-benzenesulfonylmethyl)-5-phenyl-penta...)
Affinity DataIC50: 100nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100089(2-(4-Benzoyl-benzenesulfonylmethyl)-5-phenyl-penta...)
Affinity DataIC50: 15nMAssay Description:Inhibition of MMP-8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100089(2-(4-Benzoyl-benzenesulfonylmethyl)-5-phenyl-penta...)
Affinity DataIC50: 4nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100089(2-(4-Benzoyl-benzenesulfonylmethyl)-5-phenyl-penta...)
Affinity DataIC50: 5nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed