BDBM50100087 5-Phenyl-2-[4-(pyridine-4-carbonyl)-benzenesulfonylmethyl]-pentanoic acid hydroxyamide; hydrochloride::CHEMBL542088

SMILES ONC(=O)C(CCCc1ccccc1)CS(=O)(=O)c1ccc(cc1)C(=O)c1ccncc1

InChI Key InChIKey=FFXPIMSNULYFOV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50100087   

TargetInterstitial collagenase(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100087(5-Phenyl-2-[4-(pyridine-4-carbonyl)-benzenesulfony...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100087(5-Phenyl-2-[4-(pyridine-4-carbonyl)-benzenesulfony...)
Affinity DataIC50: 15nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100087(5-Phenyl-2-[4-(pyridine-4-carbonyl)-benzenesulfony...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100087(5-Phenyl-2-[4-(pyridine-4-carbonyl)-benzenesulfony...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100087(5-Phenyl-2-[4-(pyridine-4-carbonyl)-benzenesulfony...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed