BDBM50100086 CHEMBL33977::[2,6-Dimethyl-4-(3-methyl-4-oxo-3,4-dihydro-phthalazin-1-yl)-phenoxy]-acetic acid methyl ester

SMILES COC(=O)COc1c(C)cc(cc1C)-c1nn(C)c(=O)c2ccccc12

InChI Key InChIKey=FDJBYAHLPYLRKD-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50100086   

TargetNeutrophil collagenase(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100086([2,6-Dimethyl-4-(3-methyl-4-oxo-3,4-dihydro-phthal...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100086([2,6-Dimethyl-4-(3-methyl-4-oxo-3,4-dihydro-phthal...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100086([2,6-Dimethyl-4-(3-methyl-4-oxo-3,4-dihydro-phthal...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100086([2,6-Dimethyl-4-(3-methyl-4-oxo-3,4-dihydro-phthal...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Celltech-Chiroscience

Curated by ChEMBL
LigandPNGBDBM50100086([2,6-Dimethyl-4-(3-methyl-4-oxo-3,4-dihydro-phthal...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed