BDBM50099867 CHEMBL28570::Sodium; (E)-2-amino-5-(4-isopropyl-phenyl)-5-pyridin-3-yl-pent-4-enoate

SMILES CC(C)c1ccc(cc1)C(=C/CC(N)C([O-])=O)\c1cccnc1

InChI Key InChIKey=RBQHMQONLZLENY-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099867   

TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099867(Sodium; (E)-2-amino-5-(4-isopropyl-phenyl)-5-pyrid...)
Affinity DataIC50: 6.48E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 2(Rat)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099867(Sodium; (E)-2-amino-5-(4-isopropyl-phenyl)-5-pyrid...)
Affinity DataIC50: 5.93E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed