BDBM50099865 CHEMBL283017::Sodium; 2-amino-5,5-bis-(4-isopropyl-phenyl)-pent-4-enoate

SMILES [#6]-[#6](-[#6])-c1ccc(cc1)-[#6](=[#6]/[#6]-[#6](-[#7])-[#6](-[#8-])=O)\c1ccc(cc1)-[#6](-[#6])-[#6]

InChI Key InChIKey=XRVRKVGQXWILID-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099865   

TargetSodium- and chloride-dependent glycine transporter 2(Rat)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099865(Sodium; 2-amino-5,5-bis-(4-isopropyl-phenyl)-pent-...)
Affinity DataIC50: 2.03E+3nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-2 (GlyT-2) transporter cells after incubation at 30 degrees for 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed
TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099865(Sodium; 2-amino-5,5-bis-(4-isopropyl-phenyl)-pent-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro glycine reuptake inhibitory activity against glycine transporter type-1 isoform C (GlyT-1c) transporter cells after incubation at 30 degrees...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed