BDBM50099736 4-Ethoxy-[1,2]naphthoquinone::4-ethoxynaphthalene-1,2-dione::CHEMBL50620

SMILES CCOC1=CC(=O)C(=O)c2ccccc12

InChI Key InChIKey=XPXODXIULRDWNT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50099736   

TargetReceptor-type tyrosine-protein phosphatase C(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099736(4-ethoxynaphthalene-1,2-dione | 4-Ethoxy-[1,2]naph...)
Affinity DataIC50: 2.00E+3nMAssay Description:In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 2(Human)
Virginia Polytechnic Institute and State University

Curated by ChEMBL
LigandPNGBDBM50099736(4-ethoxynaphthalene-1,2-dione | 4-Ethoxy-[1,2]naph...)
Affinity DataIC50: 270nMAssay Description:Inhibition of histidine-tagged human recombinant Cdc25B catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 1(Mouse)
Virginia Polytechnic Institute and State University

Curated by ChEMBL
LigandPNGBDBM50099736(4-ethoxynaphthalene-1,2-dione | 4-Ethoxy-[1,2]naph...)
Affinity DataIC50: 820nMAssay Description:Inhibition of histidine-tagged mouse MKP1 catalytic domain expressed in human Hela cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDual specificity protein phosphatase 6(Rat)
Virginia Polytechnic Institute and State University

Curated by ChEMBL
LigandPNGBDBM50099736(4-ethoxynaphthalene-1,2-dione | 4-Ethoxy-[1,2]naph...)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of histidine-tagged rat recombinant MKP3 catalytic domain expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed