BDBM50099692 CHEMBL51314::N-(9,10-Dioxo-9,10-dihydro-phenanthren-2-yl)-2,2-dimethyl-propionamide::N-(9,10-Dioxo-9,10-dihydro-phenanthrene-2-yl)-2,2-dimethyl-propionamide::N-(9,10-dioxo-9,10-dihydrophenanthren-2-yl)-2,2-dimethylpropionamide

SMILES CC(C)(C)C(=O)Nc1ccc-2c(c1)C(=O)C(=O)c1ccccc-21

InChI Key InChIKey=VZQDDSYKVYARDW-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50099692   

TargetReceptor-type tyrosine-protein phosphatase C(Human)
United States Army Medical Research Institute of Infectious Diseases

LigandPNGBDBM50099692(N-(9,10-Dioxo-9,10-dihydro-phenanthrene-2-yl)-2,2-...)
Affinity DataIC50: 400nMAssay Description:Protein phosphatases were purchased from Upstate Biotechnology (Lake Placid, NY).More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(N-(9,10-Dioxo-9,10-dihydro-phenanthrene-2-yl)-2,2-...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibitory concentration against FAP-1 pNPPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(N-(9,10-Dioxo-9,10-dihydro-phenanthrene-2-yl)-2,2-...)
Affinity DataIC50: 400nMAssay Description:Inhibitory concentration against Cathepsin SMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
United States Army Medical Research Institute of Infectious Diseases

LigandPNGBDBM50099692(N-(9,10-Dioxo-9,10-dihydro-phenanthrene-2-yl)-2,2-...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibitory concentration against CD45 protein-tyrosine phosphatase using lck-10 mer as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(N-(9,10-Dioxo-9,10-dihydro-phenanthrene-2-yl)-2,2-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against FAP-1 using lck-10 mer as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(N-(9,10-Dioxo-9,10-dihydro-phenanthrene-2-yl)-2,2-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against PTP1B using lck as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(N-(9,10-Dioxo-9,10-dihydro-phenanthrene-2-yl)-2,2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
United States Army Medical Research Institute of Infectious Diseases

LigandPNGBDBM50099692(N-(9,10-Dioxo-9,10-dihydro-phenanthrene-2-yl)-2,2-...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(N-(9,10-Dioxo-9,10-dihydro-phenanthrene-2-yl)-2,2-...)
Affinity DataIC50: 500nMAssay Description:Inhibitory concentration against Cathepsin LMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50099692(N-(9,10-Dioxo-9,10-dihydro-phenanthrene-2-yl)-2,2-...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of Lck phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(N-(9,10-Dioxo-9,10-dihydro-phenanthrene-2-yl)-2,2-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of protein tyrosine phosphatase N1 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(N-(9,10-Dioxo-9,10-dihydro-phenanthrene-2-yl)-2,2-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of protein tyrosine phosphatase N13 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Astrazeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099692(N-(9,10-Dioxo-9,10-dihydro-phenanthrene-2-yl)-2,2-...)
Affinity DataIC50: 950nMAssay Description:Inhibition of 6xHis-tagged PTP1B (unknown origin) Escherichia coli BL21 (DE3)-RIL using OMFP as substrate incubated for 30 mins by fluorescence based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed