BDBM50099567 (3S,4R)-Ethanesulfonic acid (6-cyano-3-hydroxy-2,2-dimethyl-chroman-4-yl)-methyl-amide::CHEMBL44297::Ethanesulfonic acid (6-cyano-3-hydroxy-2,2-dimethyl-chroman-4-yl)-methyl-amide

SMILES CCS(=O)(=O)N(C)[C@H]1[C@H](O)C(C)(C)Oc2ccc(cc12)C#N

InChI Key InChIKey=HVSJHHXUORMCGK-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50099567   

TargetPotassium voltage-gated channel subfamily E/KQT member 1(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50099567(Ethanesulfonic acid (6-cyano-3-hydroxy-2,2-dimethy...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytes,(Experiment 2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily E/KQT member 1(Human)
Aventis Pharma Deutschland

Curated by ChEMBL
LigandPNGBDBM50099567(Ethanesulfonic acid (6-cyano-3-hydroxy-2,2-dimethy...)
Affinity DataIC50: 4.45E+4nMAssay Description:Inhibition of human IKs-channel expressed in Xenopus oocytes,(Experiment 1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
Prestwick Chemical

Curated by ChEMBL
LigandPNGBDBM50099567(Ethanesulfonic acid (6-cyano-3-hydroxy-2,2-dimethy...)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of guinea pig Iks potassium channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily D member 3(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50099567(Ethanesulfonic acid (6-cyano-3-hydroxy-2,2-dimethy...)
Affinity DataIC50: 1.40E+3nMAssay Description:The inhibitory concentration for 50% was measured on potassium channel complexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Guinea pig)
Prestwick Chemical

Curated by ChEMBL
LigandPNGBDBM50099567(Ethanesulfonic acid (6-cyano-3-hydroxy-2,2-dimethy...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of guinea pig Iks potassium channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed