BDBM50099562 (3aS,9bR)-1-Methyl-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo[3,2-h]isoquinoline::CHEMBL417278

SMILES CN1CC[C@@H]2CCc3ccncc3[C@H]12

InChI Key InChIKey=ZZGFWRKTYORFQP-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50099562   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50099562((3aS,9bR)-1-Methyl-2,3,3a,4,5,9b-hexahydro-1H-pyrr...)
Affinity DataEC50:  4.40E+4nMAssay Description:Effective concentration against rat alpha7 nicotinic acetylcholine receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50099562((3aS,9bR)-1-Methyl-2,3,3a,4,5,9b-hexahydro-1H-pyrr...)
Affinity DataKi:  400nMAssay Description:Inhibition of [3H]nicotine binding to alpha4-beta2 nicotinic acetylcholine receptor of rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-2(Rat)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50099562((3aS,9bR)-1-Methyl-2,3,3a,4,5,9b-hexahydro-1H-pyrr...)
Affinity DataKi:  400nMAssay Description:Affinity for Nicotinic acetylcholine receptor alpha4-beta2 tested by analogue-induced inhibition of [3H]NIC binding to rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50099562((3aS,9bR)-1-Methyl-2,3,3a,4,5,9b-hexahydro-1H-pyrr...)
Affinity DataKi:  590nMAssay Description:Inhibition of [3H]-MLA binding to alpha-7 nicotinic acetylcholine receptor of rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50099562((3aS,9bR)-1-Methyl-2,3,3a,4,5,9b-hexahydro-1H-pyrr...)
Affinity DataKi:  590nMAssay Description:Affinity for alpha-7 neuronal nicotinic acetylcholine receptor subtype determined by inhibition of [3H]-MLA binding to rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed