BDBM50099382 4-Chloro-5-(4-chloro-phenylsulfanyl)-2-methyl-6-(4-methyl-piperazin-1-yl)-pyrimidine::CHEMBL14998

SMILES CN1CCN(CC1)c1nc(C)nc(Cl)c1Sc1ccc(Cl)cc1

InChI Key InChIKey=JXJXUPSKYPWNKB-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50099382   

TargetD(2) dopamine receptor(Human)
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099382(4-Chloro-5-(4-chloro-phenylsulfanyl)-2-methyl-6-(4...)
Affinity DataKi:  62nMAssay Description:Binding affinity to Dopamine receptor D2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099382(4-Chloro-5-(4-chloro-phenylsulfanyl)-2-methyl-6-(4...)
Affinity DataKi:  260nMAssay Description:Binding affinity to Dopamine receptor D4 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Sumitomo Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099382(4-Chloro-5-(4-chloro-phenylsulfanyl)-2-methyl-6-(4...)
Affinity DataKi:  1.50E+3nMAssay Description:Binding affinity to 5-hydroxytryptamine 1A receptor was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed