BDBM50099233 1-[3-(6-Isopropyl-naphthalen-2-yl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-yl]-propan-1-one::CHEMBL416058

SMILES CCC(=O)C1C2CCC(CC1c1ccc3cc(ccc3c1)C(C)C)N2C

InChI Key

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50099233   

TargetSodium-dependent dopamine transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50099233(1-[3-(6-Isopropyl-naphthalen-2-yl)-8-methyl-8-aza-...)
Affinity DataIC50: 0.390nMAssay Description:Inhibitory activity in displacing [125I]- RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
State University of New York

Curated by ChEMBL
LigandPNGBDBM50099233(1-[3-(6-Isopropyl-naphthalen-2-yl)-8-methyl-8-aza-...)
Affinity DataKi:  1.97nMAssay Description:Affinity for the displacement of [3H]paroxetine binding to serotonin transporter (SERT) in rat frontal cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed