BDBM50099023 CHEMBL11149::N-[4-(4-{2-[2-(3,5-Dimethyl-phenyl)-1H-indol-3-yl]-ethylamino}-butyl)-phenyl]-methanesulfonamide::N-[4-(4-{2-[2-(3,5-Dimethyl-phenyl)-2,3-dihydro-1H-indol-3-yl]-ethylamino}-butyl)-phenyl]-methanesulfonamide

SMILES Cc1cc(C)cc(c1)-c1[nH]c2ccccc2c1CCNCCCCc1ccc(NS(C)(=O)=O)cc1

InChI Key InChIKey=RRLFSIAYEBCALH-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50099023   

TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099023(N-[4-(4-{2-[2-(3,5-Dimethyl-phenyl)-1H-indol-3-yl]...)
Affinity DataIC50: 7nMAssay Description:Inhibition of rat GnRH receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099023(N-[4-(4-{2-[2-(3,5-Dimethyl-phenyl)-1H-indol-3-yl]...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human Gonadotropin-releasing hormone receptor bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099023(N-[4-(4-{2-[2-(3,5-Dimethyl-phenyl)-1H-indol-3-yl]...)
Affinity DataIC50: 7nMAssay Description:Inhibition of rat gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099023(N-[4-(4-{2-[2-(3,5-Dimethyl-phenyl)-1H-indol-3-yl]...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity evaluated against human Gonadotropin-releasing hormone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099023(N-[4-(4-{2-[2-(3,5-Dimethyl-phenyl)-1H-indol-3-yl]...)
Affinity DataIC50: 7nMAssay Description:Inhibition of [125I]buserelin binding to rat pituitary Gonadotropin-releasing hormone receptor, in the absence of bovine serum albumin (BSA)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099023(N-[4-(4-{2-[2-(3,5-Dimethyl-phenyl)-1H-indol-3-yl]...)
Affinity DataIC50: 7nMAssay Description:Inhibitory activity against human GnRH receptor using des-Gly10[125I]Tyr5, D-Leu, NMeLeu, Pro-NEt]GnRH radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50099023(N-[4-(4-{2-[2-(3,5-Dimethyl-phenyl)-1H-indol-3-yl]...)
Affinity DataIC50: 170nMAssay Description:Binding affinity against gonadotropin-releasing hormone receptor of ratMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed