BDBM50099011 1-Methyl-cyclohexanecarboxylic acid {(R)-2-[4-(4-methoxy-[1,2,5]thiadiazol-3-yl)-piperazin-1-yl]-1-pyridin-3-ylmethyl-ethyl}-amide::CHEMBL266393

SMILES COc1nsnc1N1CCN(C[C@@H](Cc2cccnc2)NC(=O)C2(C)CCCCC2)CC1

InChI Key InChIKey=SWKBPFACSXLZFM-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50099011   

TargetD(2) dopamine receptor(Rat)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099011(1-Methyl-cyclohexanecarboxylic acid {(R)-2-[4-(4-m...)
Affinity DataIC50: 3.52E+3nMAssay Description:Percent inhibition towards dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(4) dopamine receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099011(1-Methyl-cyclohexanecarboxylic acid {(R)-2-[4-(4-m...)
Affinity DataIC50: 1.10E+3nMAssay Description:Percent inhibition towards dopamine D4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099011(1-Methyl-cyclohexanecarboxylic acid {(R)-2-[4-(4-m...)
Affinity DataIC50: 489nMAssay Description:Percent inhibition towards dopamine D3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50099011(1-Methyl-cyclohexanecarboxylic acid {(R)-2-[4-(4-m...)
Affinity DataKi:  3nMAssay Description:Ability to displace [3H]8-OH-DPAT from CHO cells stably transfected with human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed