BDBM50098923 (3R,9aS)-2-(4-Methoxy-benzenesulfonyl)-5-oxo-octahydro-pyrrolo[1,2-a][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL6572

SMILES COc1ccc(cc1)S(=O)(=O)N1C[C@@H]2CCCN2C(=O)C[C@@H]1C(=O)NO

InChI Key InChIKey=QPEZTCMCOIDQRV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50098923   

TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098923((3R,9aS)-2-(4-Methoxy-benzenesulfonyl)-5-oxo-octah...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098923((3R,9aS)-2-(4-Methoxy-benzenesulfonyl)-5-oxo-octah...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetCollagenase 3(Rat)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098923((3R,9aS)-2-(4-Methoxy-benzenesulfonyl)-5-oxo-octah...)
Affinity DataIC50: 2nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098923((3R,9aS)-2-(4-Methoxy-benzenesulfonyl)-5-oxo-octah...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed