BDBM50098920 (R)-4-(4-Methoxy-benzenesulfonyl)-1-(1-methyl-1H-imidazole-4-sulfonyl)-[1,4]diazepane-5-carboxylic acid hydroxyamide::CHEMBL268114

SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC[C@@H]1C(=O)NO)S(=O)(=O)c1cn(C)cn1

InChI Key InChIKey=CNDCCBOSTVCBMM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50098920   

TargetCollagenase 3(Rat)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098920((R)-4-(4-Methoxy-benzenesulfonyl)-1-(1-methyl-1H-i...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098920((R)-4-(4-Methoxy-benzenesulfonyl)-1-(1-methyl-1H-i...)
Affinity DataIC50: 346nMAssay Description:Inhibition of human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098920((R)-4-(4-Methoxy-benzenesulfonyl)-1-(1-methyl-1H-i...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098920((R)-4-(4-Methoxy-benzenesulfonyl)-1-(1-methyl-1H-i...)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098920((R)-4-(4-Methoxy-benzenesulfonyl)-1-(1-methyl-1H-i...)
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098920((R)-4-(4-Methoxy-benzenesulfonyl)-1-(1-methyl-1H-i...)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098920((R)-4-(4-Methoxy-benzenesulfonyl)-1-(1-methyl-1H-i...)
Affinity DataIC50: 39nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed