BDBM50098919 (R)-1-Isopropyl-4-(4-methoxy-benzenesulfonyl)-7-oxo-[1,4]diazepane-5-carboxylic acid hydroxyamide::CHEMBL7756

SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(C(C)C)C(=O)C[C@@H]1C(=O)NO

InChI Key InChIKey=HTNLSTWGHBHDPS-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50098919   

TargetCollagenase 3(Rat)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098919((R)-1-Isopropyl-4-(4-methoxy-benzenesulfonyl)-7-ox...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098919((R)-1-Isopropyl-4-(4-methoxy-benzenesulfonyl)-7-ox...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098919((R)-1-Isopropyl-4-(4-methoxy-benzenesulfonyl)-7-ox...)
Affinity DataIC50: 369nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098919((R)-1-Isopropyl-4-(4-methoxy-benzenesulfonyl)-7-ox...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098919((R)-1-Isopropyl-4-(4-methoxy-benzenesulfonyl)-7-ox...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098919((R)-1-Isopropyl-4-(4-methoxy-benzenesulfonyl)-7-ox...)
Affinity DataIC50: 4.10nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098919((R)-1-Isopropyl-4-(4-methoxy-benzenesulfonyl)-7-ox...)
Affinity DataIC50: 22nMAssay Description:Inhibition of human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed