BDBM50098914 (R)-5-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfonyl)-[1,4]diazepane-1-carboxylic acid benzyl ester::CHEMBL267939

SMILES COc1ccc(cc1)S(=O)(=O)N1CCN(CC[C@@H]1C(=O)NO)C(=O)OCc1ccccc1

InChI Key InChIKey=XDYZXHJJAIXYOR-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50098914   

TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098914((R)-5-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfony...)
Affinity DataIC50: 97nMAssay Description:Inhibition of human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098914((R)-5-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfony...)
Affinity DataIC50: 737nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098914((R)-5-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfony...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098914((R)-5-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfony...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098914((R)-5-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfony...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098914((R)-5-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfony...)
Affinity DataIC50: 14nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetCollagenase 3(Rat)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098914((R)-5-Hydroxycarbamoyl-4-(4-methoxy-benzenesulfony...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed