BDBM50098913 (R)-1,4-Bis-(4-methoxy-benzenesulfonyl)-[1,4]diazepane-5-carboxylic acid hydroxyamide::CHEMBL427616

SMILES COc1ccc(cc1)S(=O)(=O)N1CC[C@@H](N(CC1)S(=O)(=O)c1ccc(OC)cc1)C(=O)NO

InChI Key InChIKey=KKVTZTBYJGHGCO-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50098913   

TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098913((R)-1,4-Bis-(4-methoxy-benzenesulfonyl)-[1,4]diaze...)
Affinity DataIC50: 29nMAssay Description:Inhibition of human Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetCollagenase 3(Rat)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098913((R)-1,4-Bis-(4-methoxy-benzenesulfonyl)-[1,4]diaze...)
Affinity DataIC50: 0.840nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098913((R)-1,4-Bis-(4-methoxy-benzenesulfonyl)-[1,4]diaze...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098913((R)-1,4-Bis-(4-methoxy-benzenesulfonyl)-[1,4]diaze...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098913((R)-1,4-Bis-(4-methoxy-benzenesulfonyl)-[1,4]diaze...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098913((R)-1,4-Bis-(4-methoxy-benzenesulfonyl)-[1,4]diaze...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of Matrix metalloprotease-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098913((R)-1,4-Bis-(4-methoxy-benzenesulfonyl)-[1,4]diaze...)
Affinity DataIC50: 905nMAssay Description:Inhibition of Matrix metalloprotease-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098913((R)-1,4-Bis-(4-methoxy-benzenesulfonyl)-[1,4]diaze...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of MMP-9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098913((R)-1,4-Bis-(4-methoxy-benzenesulfonyl)-[1,4]diaze...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of MMP-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098913((R)-1,4-Bis-(4-methoxy-benzenesulfonyl)-[1,4]diaze...)
Affinity DataIC50: 29nMAssay Description:Inhibition of MMP-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetStromelysin-1(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098913((R)-1,4-Bis-(4-methoxy-benzenesulfonyl)-[1,4]diaze...)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of MMP-3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098913((R)-1,4-Bis-(4-methoxy-benzenesulfonyl)-[1,4]diaze...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of MMP-8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCollagenase 3(Rat)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098913((R)-1,4-Bis-(4-methoxy-benzenesulfonyl)-[1,4]diaze...)
Affinity DataIC50: 0.840nMAssay Description:Inhibition of rat MMP-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMatrilysin(Human)
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50098913((R)-1,4-Bis-(4-methoxy-benzenesulfonyl)-[1,4]diaze...)
Affinity DataIC50: 905nMAssay Description:Inhibition of MMP-7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed