BDBM50098793 CHEMBL3593342

SMILES CC(C)(C)c1cc(no1)C(=O)C(=N\Nc1cc(Cl)c(Cl)c(Cl)c1)\C#N

InChI Key InChIKey=BVFFSUDSERHSKS-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50098793   

TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50098793(CHEMBL3593342)
Affinity DataIC50: 900nMAssay Description:Displacement of 8-NBD-cAMP from mouse recombinant EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50098793(CHEMBL3593342)
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at human recombinant EPAC1 assessed as inhibition of Rap1b-bGDP exchange activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2016
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50098793(CHEMBL3593342)
Affinity DataIC50: 2.70E+3nMAssay Description:Antagonist activity at recombinant human full length EPAC1 assessed as inhibition of EPAC1-mediated Rap1B (1 to 167 residues)-BODIPY GDP nucleotide e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2019
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 3(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50098793(CHEMBL3593342)
Affinity DataIC50: 2.40E+3nMAssay Description:Displacement of 8-NBD-cAMP from recombinant human EPAC1 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Mouse)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50098793(CHEMBL3593342)
Affinity DataIC50: 900nMAssay Description:Displacement of 8-NBD-cAMP from mouse EPAC2 by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed