BDBM50098325 9-(4-{4-[(4'-Trifluoromethyl-biphenyl-2-carbonyl)-amino]-benzoimidazol-1-yl}-butyl)-9H-fluorene-9-carboxylic acid (2,2,2-trifluoro-ethyl)-amide::CHEMBL353385

SMILES FC(F)(F)CNC(=O)C1(CCCCn2cnc3c(NC(=O)c4ccccc4-c4ccc(cc4)C(F)(F)F)cccc23)c2ccccc2-c2ccccc12

InChI Key InChIKey=WFOHFXRVZBRLFW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50098325   

TargetMicrosomal triglyceride transfer protein large subunit(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098325(9-(4-{4-[(4'-Trifluoromethyl-biphenyl-2-carbonyl)-...)
Affinity DataIC50: 0.240nMAssay Description:In vitro inhibition of human microsomal triglyceride transfer protein in HepG2 cells using apoB secretion assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMicrosomal triglyceride transfer protein large subunit(Human)
The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098325(9-(4-{4-[(4'-Trifluoromethyl-biphenyl-2-carbonyl)-...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibition of human Microsomal Triglyceride Transfer Protein (triglyceride transfer assay)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed