BDBM50098222 4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid (tetrahydro-furan-2-ylmethyl)-amide::CHEMBL8410

SMILES CCn1ncc2c(NCc3ccc(OC)c(Cl)c3)c(cnc12)C(=O)NC[C@@H]1CCCO1

InChI Key InChIKey=IIJWWYFKEQWSRO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50098222   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50098222(4-(3-Chloro-4-methoxy-benzylamino)-1-ethyl-1H-pyra...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of PDE5 of human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed