BDBM50097909 1-[3-(5-Fluoro-1H-indol-3-yl)-ethyl]-4-(methylsulfinyl)benzene-piperidin-4-ol::4-(oxidosulfanyl)benzenemethyl-1-[2-(5-fluoro-1H-indol-3-yl)-ethyl]-piperidin-4-ol::CHEMBL59413

SMILES OC1(C[S@@](=O)c2ccccc2)CCN(CCc2c[nH]c3ccc(F)cc23)CC1

InChI Key InChIKey=VWIWOPFCNLLGBQ-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097909   

TargetSubstance-K receptor(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50097909(4-(oxidosulfanyl)benzenemethyl-1-[2-(5-fluoro-1H-i...)
Affinity DataIC50: 22nMAssay Description:Binding affinity for heterologously expressed human Tachykinin receptor 2 using [3H]-SR- 48968 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSubstance-K receptor(Rat)TBA
LigandPNGBDBM50097909(4-(oxidosulfanyl)benzenemethyl-1-[2-(5-fluoro-1H-i...)
Affinity DataKi:  3.98nMAssay Description:Binding affinity by displacement of radiolabeled GR-100679 from Tachykinin receptor 2 from homogenized rat colonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2018
Entry Details

TargetSubstance-K receptor(Rat)TBA
LigandPNGBDBM50097909(4-(oxidosulfanyl)benzenemethyl-1-[2-(5-fluoro-1H-i...)
Affinity DataKi:  4nMAssay Description:Binding affinity by displacement of radiolabeled GR-100679 from Tachykinin receptor 2 from homogenized rat colonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2018
Entry Details

TargetNeuromedin-K receptor(Guinea pig)TBA
LigandPNGBDBM50097909(4-(oxidosulfanyl)benzenemethyl-1-[2-(5-fluoro-1H-i...)
Affinity DataKi:  3.98E+4nMAssay Description:Tested for inhibition of binding of [3H]senktide to Tachykinin receptor 3 in guinea pig cerebral cortex membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2018
Entry Details