BDBM50097886 (1-Hydroxy-1-phosphono-octyl)-phosphonic acid::1-hydroxyoctane-1,1-diyldiphosphonic acid::CHEMBL298547

SMILES CCCCCCCC(O)(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=ITCAYUFDTCVNTE-UHFFFAOYSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50097886   

TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50097886(1-hydroxyoctane-1,1-diyldiphosphonic acid | (1-Hyd...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibitory activity against the human recombinant geranylgeranyl diphosphate synthase (GGPPSase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50097886(1-hydroxyoctane-1,1-diyldiphosphonic acid | (1-Hyd...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyprenyl synthetase family protein(Leishmania donovani)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50097886(1-hydroxyoctane-1,1-diyldiphosphonic acid | (1-Hyd...)
Affinity DataIC50: 1.99E+4nMAssay Description:Inhibitory activity against Leishmania major Farnesyl diphosphate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50097886(1-hydroxyoctane-1,1-diyldiphosphonic acid | (1-Hyd...)
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibitory concentration against Trypanosoma brucei farnesyl pyrophosphate synthase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50097886(1-hydroxyoctane-1,1-diyldiphosphonic acid | (1-Hyd...)
Affinity DataIC50: 9.36E+3nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl pyrophosphate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50097886(1-hydroxyoctane-1,1-diyldiphosphonic acid | (1-Hyd...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME (M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50097886(1-hydroxyoctane-1,1-diyldiphosphonic acid | (1-Hyd...)
Affinity DataKi:  980nMAssay Description:Binding affinity towards Trypanosoma cruzi farnesyl pyrophosphate synthase (TcFPPS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50097886(1-hydroxyoctane-1,1-diyldiphosphonic acid | (1-Hyd...)
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed