BDBM50097884 (1-hydroxy-1-phosphono-butyl)-phosphonic acid::1-hydroxybutane-1,1-diyldiphosphonic acid::CHEMBL52761

SMILES CCCC(O)(P(O)(O)=O)P(O)(O)=O

InChI Key InChIKey=RUPZRJCPTQGQRU-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50097884   

TargetFarnesyl pyrophosphate synthase(Human)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50097884(1-hydroxybutane-1,1-diyldiphosphonic acid | (1-hyd...)
Affinity DataIC50: 4.28E+4nMAssay Description:Inhibition of Trypanosoma cruzi farnesyl pyrophosphate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50097884(1-hydroxybutane-1,1-diyldiphosphonic acid | (1-hyd...)
Affinity DataIC50: 6.20E+5nMAssay Description:Inhibitory activity against the human recombinant geranylgeranyl diphosphate synthase (GGPPSase).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyprenyl synthetase family protein(Leishmania donovani)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50097884(1-hydroxybutane-1,1-diyldiphosphonic acid | (1-hyd...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against Leishmania major Farnesyl diphosphate synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetH(+)-exporting diphosphatase(Trypanosoma brucei)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50097884(1-hydroxybutane-1,1-diyldiphosphonic acid | (1-hyd...)
Affinity DataIC50: 2.15E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei soluble vacuolar pyrophosphatase expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2012
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50097884(1-hydroxybutane-1,1-diyldiphosphonic acid | (1-hyd...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against Trypanosoma brucei farnesyl pyrophosphate synthase activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50097884(1-hydroxybutane-1,1-diyldiphosphonic acid | (1-hyd...)
Affinity DataKi:  5.04E+3nMAssay Description:Binding affinity towards Trypanosoma cruzi farnesyl pyrophosphate synthase (TcFPPS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed