BDBM50097867 CHEMBL3589660

SMILES OC(=O)c1nc2ccccc2c2[nH]c3c(Cl)cccc3c12

InChI Key InChIKey=ABRIIMZXUFHPCH-UHFFFAOYSA-N

Data  16 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50097867   

TargetDual specificity protein kinase CLK2(Mouse)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097867(CHEMBL3589660)
Affinity DataIC50: 61nMAssay Description:Inhibition of mouse recombinant CLK2 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Mouse)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097867(CHEMBL3589660)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse recombinant CLK3 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK4(Mouse)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097867(CHEMBL3589660)
Affinity DataIC50: 45nMAssay Description:Inhibition of mouse recombinant CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1B(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097867(CHEMBL3589660)
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant DYRK1B expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097867(CHEMBL3589660)
Affinity DataIC50: 40nMAssay Description:Inhibition of human recombinant DYRK2 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097867(CHEMBL3589660)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097867(CHEMBL3589660)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human recombinant CDK9 expressed in insect cells using CDK7/9 tide as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK1(Mouse)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097867(CHEMBL3589660)
Affinity DataIC50: 130nMAssay Description:Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 3(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097867(CHEMBL3589660)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant DYRK3 expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097867(CHEMBL3589660)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK2 using [gamma-33P]ATP as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097867(CHEMBL3589660)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK5 using [gamma-33P]ATP as substrate after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097867(CHEMBL3589660)
Affinity DataIC50: 31nMAssay Description:Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/24/2016
Entry Details Article
PubMed
TargetDual specificity protein kinase CLK3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50097867(CHEMBL3589660)
Affinity DataIC50: 100nMAssay Description:Inhibition of human CLK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50097867(CHEMBL3589660)
Affinity DataIC50: 130nMAssay Description:Inhibition of human CLK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Technische Universit£T Braunschweig

Curated by ChEMBL
LigandPNGBDBM50097867(CHEMBL3589660)
Affinity DataIC50: 61nMAssay Description:Inhibition of human DYRK1AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity protein kinase CLK4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50097867(CHEMBL3589660)
Affinity DataIC50: 45nMAssay Description:Inhibition of human CLK4More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed