BDBM50097810 (S)-2-({5-[(3-Biphenyl-4-ylmethyl-3H-imidazol-4-ylmethyl)-amino]-biphenyl-2-carbonyl}-amino)-4-methylsulfanyl-butyric acid::CHEMBL344687

SMILES CSCC[C@H](NC(=O)c1ccc(NCc2cncn2Cc2ccc(cc2)-c2ccccc2)cc1-c1ccccc1)C(O)=O

InChI Key InChIKey=BKSIKSJVVZGDPT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50097810   

LigandPNGBDBM50097810((S)-2-({5-[(3-Biphenyl-4-ylmethyl-3H-imidazol-4-yl...)
Affinity DataIC50: 260nMAssay Description:Inhibition of mammalian FarnesyltransferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDimer of Protein farnesyltransferase subunit beta(Human)
Yale University

Curated by ChEMBL
LigandPNGBDBM50097810((S)-2-({5-[(3-Biphenyl-4-ylmethyl-3H-imidazol-4-yl...)
Affinity DataIC50: 8nMAssay Description:Inhibition of Trypanosoma brucei protein farnesyltransferase at 50 nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50097810((S)-2-({5-[(3-Biphenyl-4-ylmethyl-3H-imidazol-4-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mammalian H-Ras processing in NIH 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed