BDBM50097587 (R)-((S)-2-Bromo-4-hydroxy-cyclohex-2-enyl)-(4'-methoxy-biphenyl-4-sulfonylamino)-acetic acid::CHEMBL158265

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N[C@H](C1CC[C@H](O)C=C1Br)C(O)=O

InChI Key InChIKey=ZXQRCQILIYTPOF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50097587   

TargetCollagenase 3(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50097587((R)-((S)-2-Bromo-4-hydroxy-cyclohex-2-enyl)-(4'-me...)
Affinity DataIC50: 131nMAssay Description:Inhibition of Collagenase 3 (Matrix metalloprotease-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50097587((R)-((S)-2-Bromo-4-hydroxy-cyclohex-2-enyl)-(4'-me...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of Stromelysin (Matrix metalloprotease-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Florida

Curated by ChEMBL
LigandPNGBDBM50097587((R)-((S)-2-Bromo-4-hydroxy-cyclohex-2-enyl)-(4'-me...)
Affinity DataIC50: 38nMAssay Description:Inhibition of gelatinase A (Matrix metalloprotease-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed