BDBM50097372 3-((1H-imidazol-1-yl)methyl)-7-methoxy-2-phenyl-4H-chromen-4-one::3-Imidazol-1-ylmethyl-7-methoxy-2-phenyl-chromen-4-one::CHEMBL158635

SMILES COc1ccc2c(c1)oc(-c1ccccc1)c(Cn1ccnc1)c2=O

InChI Key InChIKey=IXJJJDBWGBTNJP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50097372   

TargetAromatase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097372(3-Imidazol-1-ylmethyl-7-methoxy-2-phenyl-chromen-4...)
Affinity DataIC50: 550nMAssay Description:Inhibition of CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097372(3-Imidazol-1-ylmethyl-7-methoxy-2-phenyl-chromen-4...)
Affinity DataIC50: 550nMAssay Description:Inhibition of human placental microsome cytochrome P450 19A1 aromataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097372(3-Imidazol-1-ylmethyl-7-methoxy-2-phenyl-chromen-4...)
Affinity DataIC50: 550nMAssay Description:Inhibition of CYP19More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50097372(3-Imidazol-1-ylmethyl-7-methoxy-2-phenyl-chromen-4...)
Affinity DataIC50: 124nMAssay Description:Inhibition of human adrenal corticoid CYP11B2 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Saarland University

Curated by ChEMBL
LigandPNGBDBM50097372(3-Imidazol-1-ylmethyl-7-methoxy-2-phenyl-chromen-4...)
Affinity DataIC50: 79nMAssay Description:Inhibition of human adrenal corticoid CYP11B1 expressed in chinese hamster V79 MZh cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50097372(3-Imidazol-1-ylmethyl-7-methoxy-2-phenyl-chromen-4...)
Affinity DataIC50: 550nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed