BDBM50097337 CHEMBL349996::Neamine derivative

SMILES NC1CC(N)C(OC2OC(CNC(=O)C(CCCNC(N)=N)NC(=O)c3ccc4ccc5cccc6ccc3c4c56)C(O)C(O)C2N)C(O)C1O

InChI Key InChIKey=JPEXILGJQXELHF-UHFFFAOYSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50097337   

TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50097337(Neamine derivative | CHEMBL349996)
Affinity DataIC50: 350nMAssay Description:Inhibitory activity against peptide binding to the Rev Response Element RNA IIB was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetProtein Tat(HIV-1)
Graduate School of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50097337(Neamine derivative | CHEMBL349996)
Affinity DataKd:  30nMAssay Description:Dissociation constant for TAR RNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetProtein Tat(HIV-1)
Graduate School of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50097337(Neamine derivative | CHEMBL349996)
Affinity DataIC50: 28nMAssay Description:Inhibition of Tat peptide binding to HIV-1 TAR RNAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
TargetProtein Rev(Human immunodeficiency virus type 1)
Graduate School of Bioscience and Biotechnology

Curated by ChEMBL
LigandPNGBDBM50097337(Neamine derivative | CHEMBL349996)
Affinity DataKd:  8.5nMAssay Description:Dissociation constant was determined for Rev Response Element RNA IIBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed