BDBM50097222 4-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-ylidene)-1-methyl-piperidine::CHEMBL152622

SMILES [#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccccc2-[#6]-[#6]-c2ccccc-12

InChI Key InChIKey=AYFAGRAOJPSHSH-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50097222   

TargetHistone-lysine N-methyltransferase SETD7(Human)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50097222(4-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-ylidene...)
Affinity DataIC50: 5.91E+4nMAssay Description:Inhibition of recombinant SET7/9 (unknown origin) using biotinylated histone H3-derived peptide/SAM as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50097222(4-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-ylidene...)
Affinity DataKi:  9nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor from rat forebrain using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50097222(4-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-ylidene...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat cerebral cortex 5-HT2A receptor after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed