BDBM50097215 4-Fluoren-9-ylidene-1-methyl-piperidine::CHEMBL348199

SMILES [#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccccc2-c2ccccc-12

InChI Key InChIKey=FBDXULPDOXXDAM-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50097215   

TargetHistone-lysine N-methyltransferase SETD7(Human)
Tokyo Medical and Dental University (Tmdu)

Curated by ChEMBL
LigandPNGBDBM50097215(4-Fluoren-9-ylidene-1-methyl-piperidine | CHEMBL34...)
Affinity DataIC50: 4.15E+4nMAssay Description:Inhibition of recombinant SET7/9 (unknown origin) using biotinylated histone H3-derived peptide/SAM as substrate after 60 mins by AlphaLISA assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50097215(4-Fluoren-9-ylidene-1-methyl-piperidine | CHEMBL34...)
Affinity DataKi:  199nMAssay Description:Binding affinity against 5-hydroxytryptamine 2A receptor from rat forebrain using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50097215(4-Fluoren-9-ylidene-1-methyl-piperidine | CHEMBL34...)
Affinity DataKi:  199nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat cerebral cortex 5-HT2A receptor after 30 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/6/2017
Entry Details Article
PubMed