BDBM50097114 6-chloro-N-(4-chlorophenethyl)quinazolin-4-amine::CHEMBL149800::[2-(4-Chloro-phenyl)-ethyl]-(6-chloro-quinazolin-4-yl)-amine

SMILES Clc1ccc(CCNc2ncnc3ccc(Cl)cc23)cc1

InChI Key InChIKey=AOWWUEORXDGINB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50097114   

TargetHuntingtin(Human)
Columbia University

Curated by ChEMBL
LigandPNGBDBM50097114(6-chloro-N-(4-chlorophenethyl)quinazolin-4-amine |...)
Affinity DataIC50: 3.44E+3nMAssay Description:Inhibition of Huntingtin protein aggregation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50097114(6-chloro-N-(4-chlorophenethyl)quinazolin-4-amine |...)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at rat mGluR5 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed