BDBM50097079 4-{5-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-imidazol-1-ylmethyl}-benzonitrile::CHEMBL150389

SMILES Clc1cccc(c1)N1CCN(Cc2cncn2Cc2ccc(cc2)C#N)CC1

InChI Key InChIKey=QEUCOFFUIKXUJV-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097079   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50097079(4-{5-[4-(3-Chloro-phenyl)-piperazin-1-ylmethyl]-im...)Copy SMILESCopy InChI

Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant Ras-CVIM by human farnesyl transferaseMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL