BDBM50097074 4-{5-[4-(2,3-Dimethyl-phenyl)-3-oxo-piperazin-1-ylmethyl]-imidazol-1-ylmethyl}-benzonitrile::CHEMBL150996

SMILES Cc1cccc(N2CCN(Cc3cncn3Cc3ccc(cc3)C#N)CC2=O)c1C

InChI Key InChIKey=JIBVFKRNXAJERA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50097074   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50097074(4-{5-[4-(2,3-Dimethyl-phenyl)-3-oxo-piperazin-1-yl...)Copy SMILESCopy InChI

Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of [3H]FPP incorporation into recombinant Ras-CVIM by human farnesyl transferaseMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/10/2009
Entry Details Article
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