BDBM50096778 1-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-ethyl]-phenyl}-3-[1-(4-octyl-thiazol-2-yl)-2,3-dihydro-1H-indol-5-yl]-thiourea::CHEMBL338664

SMILES CCCCCCCCc1csc(n1)N1CCc2cc(NC(=S)Nc3ccc(CCNC[C@H](O)c4cccnc4)cc3)ccc12

InChI Key InChIKey=ZCBPJVOMBQECAQ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50096778   

TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096778(1-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-...)
Affinity DataIC50: 260nMAssay Description:Binding affinity to the human beta-2 adrenergic receptor assayed using [125I]iodocyanopindolol as radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096778(1-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-...)
Affinity DataIC50: 110nMAssay Description:Binding affinity towards human Beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096778(1-{4-[2-((R)-2-Hydroxy-2-pyridin-3-yl-ethylamino)-...)
Affinity DataEC50:  5.30nMAssay Description:In vitro efficacy at human beta-3 adrenergic receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed