BDBM50096774 CHEMBL332132::Cyanoguanidine derivative

SMILES O[C@@H](CNCCc1ccc(NC(Nc2ccc3CCN(c4nc(cs4)-c4ccc(OC(F)(F)F)cc4)c3c2)=NC#N)cc1)c1cccnc1

InChI Key InChIKey=KIXNFVIBTBUZLQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50096774   

TargetBeta-2 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096774(Cyanoguanidine derivative | CHEMBL332132)
Affinity DataIC50: 710nMAssay Description:Binding affinity to the human beta-2 adrenergic receptor assayed using [125I]iodocyanopindolol as radioligand in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096774(Cyanoguanidine derivative | CHEMBL332132)
Affinity DataIC50: 620nMAssay Description:Binding affinity towards human Beta-1 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed