BDBM50096740 (R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2-oxa-7-aza-benzo[cd]pyren-1-one::CHEMBL122485

SMILES CN1CCc2ccc3c4c2[C@H]1Cc1cccc(oc3=O)c41

InChI Key InChIKey=HJZYUBCMOFCAGG-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50096740   

TargetD(2) dopamine receptor(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50096740((R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2-oxa-7-aza-be...)
Affinity DataKi:  270nMAssay Description:Displacement of [3H]raclopride from rat dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096740((R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2-oxa-7-aza-be...)
Affinity DataKi:  283nMAssay Description:In vitro binding affinity towards cloned rat 5-hydroxytryptamine 7 receptor using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096740((R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2-oxa-7-aza-be...)
Affinity DataKi:  541nMAssay Description:In vitro binding affinity towards cloned human Dopamine receptor D2A using [3H]- Raclopride as radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096740((R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2-oxa-7-aza-be...)
Affinity DataKi:  1.15E+3nMAssay Description:In vitro binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligand in rat hippocampus membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50096740((R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2-oxa-7-aza-be...)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]5-HT from rat SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50096740((R)-7-Methyl-6a,7,8,9-tetrahydro-6H-2-oxa-7-aza-be...)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from rat 5HT1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2012
Entry Details Article
PubMed