BDBM50096713 1H-Indole-3-carboxylic acid 1-aza-bicyclo[2.2.2]oct-3-yl ester::CHEMBL108799

SMILES O=C(OC1CN2CCC1CC2)c1c[nH]c2ccccc12

InChI Key

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50096713   

TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50096713(1H-Indole-3-carboxylic acid 1-aza-bicyclo[2.2.2]oc...)
Affinity DataEC50:  580nMAssay Description:Partial agonist activity at rat alpha-7 nicotinic acetylcholine receptor expressed in Xenopus oocytes assessed as induction of currentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/12/2016
Entry Details Article
PubMed
LigandPNGBDBM50096713(1H-Indole-3-carboxylic acid 1-aza-bicyclo[2.2.2]oc...)
Affinity DataEC50:  580nMAssay Description:Effective concentration that causes inhibition of alpha-7 nAChR, was determined. Values are expressed as EC50 +/- SEM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50096713(1H-Indole-3-carboxylic acid 1-aza-bicyclo[2.2.2]oc...)
Affinity DataKi:  2.30nMAssay Description:In vitro Binding affinity towards alpha-7 nAChR was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed
LigandPNGBDBM50096713(1H-Indole-3-carboxylic acid 1-aza-bicyclo[2.2.2]oc...)
Affinity DataKi:  2.60E+3nMAssay Description:In vitro Binding affinity towards Nicotinic acetylcholine receptor alpha4-beta2 was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2012
Entry Details Article
PubMed