BDBM50096653 2-(Biphenyl-4-yloxymethyl)-5-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-pentanoic acid hydroxyamide::CHEMBL318795

SMILES ONC(=O)C(CCCN1C(=O)c2ccccc2C1=O)COc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=QYMKPTMAFMKKTC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50096653   

TargetMatrix metalloproteinase-9(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096653(2-(Biphenyl-4-yloxymethyl)-5-(1,3-dioxo-1,3-dihydr...)
Affinity DataIC50: 221nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096653(2-(Biphenyl-4-yloxymethyl)-5-(1,3-dioxo-1,3-dihydr...)
Affinity DataIC50: 485nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096653(2-(Biphenyl-4-yloxymethyl)-5-(1,3-dioxo-1,3-dihydr...)
Affinity DataIC50: 82nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096653(2-(Biphenyl-4-yloxymethyl)-5-(1,3-dioxo-1,3-dihydr...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096653(2-(Biphenyl-4-yloxymethyl)-5-(1,3-dioxo-1,3-dihydr...)
Affinity DataIC50: 313nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed