BDBM50096650 2-(Biphenyl-4-yloxymethyl)-4-(2,4-dioxo-1,4-dihydro-2H-quinazolin-3-yl)-N-hydroxy-butyramide::CHEMBL100805

SMILES ONC(=O)C(CCn1c(=O)[nH]c2ccccc2c1=O)COc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=XYVVUCAHUUIYFV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50096650   

TargetMatrix metalloproteinase-9(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096650(2-(Biphenyl-4-yloxymethyl)-4-(2,4-dioxo-1,4-dihydr...)
Affinity DataIC50: 25nMAssay Description:Inhibition of Matrix metalloprotease-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096650(2-(Biphenyl-4-yloxymethyl)-4-(2,4-dioxo-1,4-dihydr...)
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of Matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096650(2-(Biphenyl-4-yloxymethyl)-4-(2,4-dioxo-1,4-dihydr...)
Affinity DataIC50: 69nMAssay Description:Inhibition of Matrix metalloprotease-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096650(2-(Biphenyl-4-yloxymethyl)-4-(2,4-dioxo-1,4-dihydr...)
Affinity DataIC50: 65nMAssay Description:Inhibition of Matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50096650(2-(Biphenyl-4-yloxymethyl)-4-(2,4-dioxo-1,4-dihydr...)
Affinity DataIC50: 24nMAssay Description:Inhibition of Matrix metalloprotease-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed