BDBM50096601 (2S,5S)-8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-7-methoxy-1-methyl-1,4,5,6-tetrahydro-2H-benzo[e][1,4]diazocin-3-one::8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-7-methoxy-1-methyl-1,4,5,6-tetrahydro-2H-benzo[e][1,4]diazocin-3-one::CHEMBL7078

SMILES CCCCCCCCC#Cc1ccc2N(C)[C@@H](C(C)C)C(=O)N[C@H](CO)Cc2c1OC

InChI Key InChIKey=DLMIREIQJNSNMF-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50096601   

TargetRAS guanyl-releasing protein 1(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50096601(8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-7-methoxy...)
Affinity DataKi:  13.9nMAssay Description:Binding affinity against RAS guanyl releasing protein using [3H]- PDBu as the labeled ligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Mouse)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50096601(8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-7-methoxy...)
Affinity DataKi:  35.1nMAssay Description:Displacement of [3H]- PDBu from Protein kinase C delta C1b domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C alpha type(Human)
Institute of Organic Chemistry

Curated by ChEMBL
LigandPNGBDBM50096601(8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-7-methoxy...)
Affinity DataKi:  46nMAssay Description:Displacement phorbol 12,13-dibutyrate(PDBU) binding from recombinant Protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Institute of Organic Chemistry

Curated by ChEMBL
LigandPNGBDBM50096601(8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-7-methoxy...)
Affinity DataKi:  91nMAssay Description:Binding affinity for protein kinase C deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Institute of Organic Chemistry

Curated by ChEMBL
LigandPNGBDBM50096601(8-Dec-1-ynyl-5-hydroxymethyl-2-isopropyl-7-methoxy...)
Affinity DataKi:  121nMAssay Description:Binding affinity for protein kinase C epsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed