BDBM50096543 1'-[4-methyl(phenyl)sulfonamido-3-phenylbutyl]spiro[2,3-dihydrobenzo[b]thiophene-1-oxide-3,4'-(hexahydropyridine)]::1'-[4-methyl(phenyl)sulfonamido-3-phenylbutyl]spiro[2,3-dihydrobenzo[b]thiophene-3,4'-(hexahydropyridine)1-oxide]::CHEMBL408438

SMILES CN(CC(CCN1CCC2(CS(=O)c3ccccc23)CC1)c1ccccc1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=VAJOGYQUKHOXAR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50096543   

TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096543(1'-[4-methyl(phenyl)sulfonamido-3-phenylbutyl]spir...)
Affinity DataIC50: 35nMAssay Description:Inhibitory activity against specific binding of [125I]-MIP-1 alpha to human CCR5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50096543(1'-[4-methyl(phenyl)sulfonamido-3-phenylbutyl]spir...)
Affinity DataIC50: 68nMAssay Description:Ability to displace [125 I]-MIP-1alpha from C-C chemokine receptor type 5 expressed on CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2012
Entry Details Article
PubMed